Deuterium isotope effects on toluene metabolism. Product release as a rate-limiting step in cytochrome P-450 catalysis

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

David J. Waxman, Christopher T. Walsh · Journal of Biological Chemistry · 1982 · 221 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Timing of the radical recombination step in cytochrome P-450 catalysis with ring-strained probes

Paul R. Ortiz de Montellano, Ralph A. Stearns · Journal of the American Chemical Society · 1987 · 162 citations

Life Sciences, Chemistry, Biocatalysis +12

Regioselectivity in the cytochromes P-450: Control by protein constraints and by chemical reactivities

Ronald E. White, Mary-Beth McCarthy, Karen D. Egeberg et al. · Archives of Biochemistry and Biophysics · 1984 · 142 citations

Life Sciences, Biochemistry, Chemistry +16

Structural and isotopic effects in hydrophobic binding measured by high-pressure liquid chromatography, a stable and highly precise model for hydrophobic interactions in biomembranes

Nobuo Tanaka, Edward R. Thornton · Journal of the American Chemical Society · 1977 · 125 citations

Natural Sciences, Biochemistry, Biophysics +11

Metabolic switching in cyctochrome P-450cam: deuterium isotope effects on regiospecificity and the monooxygenase/oxidase ratio

William M. Atkins, Stephen G. Sligar · Journal of the American Chemical Society · 1987 · 120 citations

Life Sciences, Biochemistry, Chemistry +14