Synthesis and bioactivity of some fluorine‐containing benzoyl arylureas. Part I: Insecticidal‐acaricidal products in which the aryl group bears a trifluoromethyl‐substituted alkyl or alkenyl side chain

Abstract

Abstract This paper reports the synthesis and the biological activity of benzoyl arylureas in which the aryl group bears a trifluoromethyl‐substitiited alkyl or alkenyl side chain, R. The activity of these compounds has been evaluated on larvae of S. littoralis , A. aegypti , L. decemlineata and on the eggs of T. urticae . In general: (1) the optimum insecticidal activities are achieved when the substituents on the benzoyl moiety, R 1 , and R 2 , are 2,6‐difluoro, the substituents on the aryl moiety, R 3 , are 3,5‐dichloro and R 1 , is 4‐(CHC(CI)CF 3 ); (2) the best acaricidal activity is shown when R 1 , is 2‐CI, R 2 , and R 3 , are hydrogen atoms and R 1 , is 4‐(CH 2 CH 2 CH(CI)CF 3 ); (3) the best overall activity is displayed when R 1 , is 2‐CI, R 2 is hydrogen, R 3 is 3‐chloro and R 1 is 4‐(CH 2 CH 2 CF 3 ).