Association of angiotensinogen m235t and a(-6)g gene polymorphisms with coronary heart disease with independence of essential hypertension: the procagene study

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.4K citations · Full text

Chromatin, Dna Sequencing, Molecular Biological Method +11

The Future of Genetic Studies of Complex Human Diseases

Neil Risch, Kathleen R. Merikangas · Science · 1996 · 5.4K citations

Genetics, Genetic Epidemiology, Genetic Foundation +17

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Hypertension, Healthy Subjects, Ace Genotype +20

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

François Cambien, Odette Poirier, Laure Lecerf et al. · Nature · 1992 · 1.9K citations

Deletion Polymorphism, Epidemiology, Cardiomyopathy +12

Molecular basis of human hypertension: Role of angiotensinogen

Xavier Jeunemaı̂tre, Florent Soubrier, Yuri Kotelevtsev et al. · Cell · 1992 · 1.9K citations

Molecular Pharmacology, Hypertension, Cardiovascular Disease +6