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Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer

Mo Chen, Adegoke O. Adeniji, Barry M. Twenter, Jeffrey D. Winkler, David W. Christianson, T.M. Penning

Bioorganic & Medicinal Chemistry Letters · 2012 · 66 citations · 28 references

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28

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.6K citations

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Abiraterone and Increased Survival in Metastatic Prostate Cancer

Johann S. de Bono, Christopher J. Logothetis, Arturo Molina et al. · New England Journal of Medicine · 2011 · 4.4K citations · Full text

, , +17

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

Chris Tran, Samedy Ouk, Nicola J. Clegg et al. · Science · 2009 · 2.3K citations · Full text

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Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

Bruce Montgomery, Elahe A. Mostaghel, Robert L. Vessella et al. · Cancer Research · 2008 · 1.4K citations · Full text

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Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study

Howard I. Scher, Tomasz M. Beer, Celestia S. Higano et al. · The Lancet · 2010 · 1.1K citations · Full text

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