Publication | Closed Access
Spontaneous Transformation of Human Brain Cells Grown in vitro and Description of Associated Virus Particles
47
Citations
4
References
1972
Year
Viral ReplicationDevelopmental BiologyXenotransplantationSpontaneous TransformationTransformed CellsNeurovirologyMolecular VirologyViral PathogenesisOncogenic Rna VirusesVirologyCell CultureAssociated Virus ParticlesNeuroscienceSubculture 60MedicineCell Biology
A human brain cell culture grown in vitro has spontaneously transformed, as determined by morphology, growth characteristics, and karyotype analysis. Virus particles morphologically akin to oncogenic RNA viruses are present in the transformed cells, which are now in subculture 60.
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