Concepedia

Natural mineral-rich water ingestion improves hepatic and fat glucocorticoid-signaling and increases sirtuin 1 in an animal model of metabolic syndrome

Cidália Pereira, Mílton Severo, Delminda Neves, António Ascensão, José Magalhães, João Tiago Guimarães, Rosário Monteiro, Maria João Martins

Hormone Molecular Biology and Clinical Investigation · 2015 · 14 citations · 26 references

DOI

Abstract

Glucocorticoid-signaling was different among SCAT and VAT and also in liver. Mineral-rich water modulation of fructose effects on glucocorticoid-signaling and Sirt1 underlines the better metabolic profile found earlier.

References

26

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Frédéric Picard, Martin V. Kurtev, Namjin Chung et al. · Nature · 2004 · 1.9K citations · Full text

, , +7

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

Aparna Purushotham, Thaddeus T. Schug, Qing Xu et al. · Cell Metabolism · 2009 · 1.1K citations · Full text

, , +14

Sirt1 protects against high-fat diet-induced metabolic damage

Paul T. Pfluger, Daniel Herranz, Susana Velasco-Miguel et al. · Proceedings of the National Academy of Sciences · 2008 · 923 citations · Full text

, , +14

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

Thien T. Tran, Yuji Yamamoto, Stéphane Gesta et al. · Cell Metabolism · 2008 · 690 citations · Full text

, , +5

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

Alexander S. Banks, Ning Kon, Colette M. Knight et al. · Cell Metabolism · 2008 · 625 citations · Full text

, , +11