Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Elisabetta Polazzi, Ilaria Mengoni, Marco Caprini et al. · Neurosignals · 2012 · 9K citations · Full text

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Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science · 2005 · 5.8K citations

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Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Christopher J. Phiel, Fang Zhang, Eric Yi‐Hsiu Huang et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

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Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

Robert J. Ferrante, James K. Kubilus, Junghee Lee et al. · Journal of Neuroscience · 2003 · 689 citations · Full text

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Histone Deacetylase Inhibitors Exhibit Anti-Inflammatory and Neuroprotective Effects in a Rat Permanent Ischemic Model of Stroke: Multiple Mechanisms of Action

Hyeon Ju Kim, Michael K. Rowe, Ming Ren et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 563 citations

Life Sciences, Neuroscience, Pharmacology +17