Classification of Alzheimer's disease and mild cognitive impairment by pattern recognition of EEG power and coherence

Abstract

This paper describes a methodology used to classify Alzheimer's disease (AD) and mild cognitive impairment (MCI) with high accuracy using EEG data. The sequential forward floating search (SFFS) was used to select features from relative average power for channel locations in frequency bands delta, theta, alpha, and beta, and coherence between intrahemispheric channel pairs for the same frequency ranges. The selected feature sets allowed us to achieve close to 90% classifier accuracy when classifying MCI patients and normal subjects. Our results showed that selecting features from a combined set of power and coherence features produced better results than the use of either feature independently. The combined feature set also showed better classification rates than a Bayesian classifier fusion approach.