Acquisition of Chemoresistance and EMT Phenotype Is Linked with Activation of the Endothelin A Receptor Pathway in Ovarian Carcinoma Cells - Concepedia

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Acquisition of Chemoresistance and EMT Phenotype Is Linked with Activation of the Endothelin A Receptor Pathway in Ovarian Carcinoma Cells

182

Citations

35

References

2011

Year

Laura Rosanò, Roberta Cianfrocca, Francesca Spinella, Valeriana Di Castro, Maria Rita Nicotra, Alessandro Lucidi, Gabriella Ferrandina, Pier Giorgio Natali, Anna Bagnato

Clinical Cancer Research

Abstract

Our data provide the first evidence that blockade of ET(A)R-driven EMT can overcome chemoresistance and inhibit tumor progression, improving the outcome of EOC patients' treatment.

References

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