Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

Hiromu Suzuki, Edward Gabrielson, Wei Chen et al. · Nature Genetics · 2002 · 856 citations · Full text

Medicine, Genetics, Oncology +16

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

Amir Rattner, Jen-Chih Hsieh, Philip M. Smallwood et al. · Proceedings of the National Academy of Sciences · 1997 · 586 citations

Life Sciences, Cell Biology, Molecular Biology +16

Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8

Shouwen Wang, Marie Krinks, Keming Lin et al. · Cell · 1997 · 517 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action

Paul W. Finch, Xi He, Michael J. Kelley et al. · Proceedings of the National Academy of Sciences · 1997 · 418 citations

Life Sciences, Developmental Biology, Molecular Biology +14