SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

Biao He, Liang You, Kazutsugu Uematsu, +6

Proceedings of the National Academy of Sciences

ImmunologyCell DeathCancer BiologyTumor BiologySignaling Pathway +19

A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies

Johannes R. Kratz, Jianxing He, Stephen K. Van Den Eeden, +26

The Lancet

Non-small-cell Lung CancerCancer DetectionMedicinePathologyInternational Validation Studies +9

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

Kazutsugu Uematsu, Biao He, Liang You, +3

Oncogene

Tumor BiologyDishevelled OverexpressionMedicinePathologyBronchial Neoplasm +9

Wnt Inhibitory Factor-1 Is Silenced by Promoter Hypermethylation in Human Lung Cancer

Julien Mazières, Biao He, Liang You, +7

Cancer Research

Aberrant Wnt SignalingTranscriptional RegulationAberrant ActivationOncogenic AgentMedicine +13

A Monoclonal Antibody against Wnt-1 Induces Apoptosis in Human Cancer Cells

Biao He, Liang You, Kazutsugu Uematsu, +5

Neoplasia

Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells

Liang You, Biao He, Zhidong Xu, +8

Oncogene

Tumor MicroenvironmentMedicineApoptosisCell DeathBronchial Neoplasm +6

An Antagonist of Dishevelled Protein-Protein Interaction Suppresses β-Catenin–Dependent Tumor Cell Growth

Naoaki Fujii, Liang You, Zhidong Xu, +9

Cancer Research

Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations

Biao He, Noemı́ Reguart, Liang You, +6

Oncogene

Tumor BiologyMedicineInduces ApoptosisCell DeathColorectal Cancer +7

Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma

Amie Y. Lee, Biao He, Liang You, +6

Oncogene

MedicinePathologyTumor SuppressorCancer BiologyCell Biology +2

An Anti-Wnt-2 Monoclonal Antibody Induces Apoptosis in Malignant Melanoma Cells and Inhibits Tumor Growth

Liang You, Biao He, Zhidong Xu, +9

Cancer Research

Chemoprevention StrategyApoptosisImmunologyCell DeathImmunotherapy +15