A new strategy for the synthesis of carbapenems. A formal total synthesis of (+)-thienamycin.

Thienamycin, a new .BETA.-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.

Jean S. Kahan, Frederick M. Kahan, Robert T. Goegelman et al. · The Journal of Antibiotics · 1979 · 507 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

A stereocontrolled synthesis of (+)-thienamycin

T. N. SALZMANN, Ronald W. Ratcliffe, B. G. CHRISTENSEN et al. · Journal of the American Chemical Society · 1980 · 388 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Structure and absolute configuration of thienamycin

G. ALBERS‐SCHOENBERG, Byron H. Arison, Otto D. Hensens et al. · Journal of the American Chemical Society · 1978 · 299 citations

Pharmacy, Chemistry, Medicinal Chemistry +8

An excellent reagent for the removal of the t-butyldimethylsilyl protecting group

Roger F. Newton, Derek P. Reynolds, Mark A. W. Finch et al. · Tetrahedron Letters · 1979 · 206 citations

Natural Sciences, Chemistry, Organic Chemistry +6

A novel synthesis of the carbapen-2-em ring system

Ronald W. Ratcliffe, T. N. SALZMANN, B. G. CHRISTENSEN · Tetrahedron Letters · 1980 · 163 citations

Pharmacy, Chemistry, Medicinal Chemistry +13