Construction and characterisation of a functional CD19 specific single chain Fv fragment for immunotherapy of B lineage leukaemia and lymphoma

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

A.E. Bolton, W. M. Hunter · Biochemical Journal · 1973 · 3.3K citations · Full text

Life Sciences, Biochemistry, Endocrinology +12

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Gérard I. Evan, George K. Lewis, Gary Ramsay et al. · Molecular and Cellular Biology · 1985 · 2.4K citations

Pharmacy, Cancer Biology, Molecular Biology +14

Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

Hennie R. Hoogenboom, Andrew D. Griffiths, Kevin S. Johnson et al. · Nucleic Acids Research · 1991 · 1K citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

Tore Lindmo, Epie Boven, Frank Cuttitta et al. · Journal of Immunological Methods · 1984 · 937 citations

Pharmacy, Immunology, Monoclonal Antibodies +13

Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms.

Takashi Yokota, Diane E. Milenic, Marc Whitlow et al. · PubMed · 1992 · 826 citations

Pharmacy, Oncology, Pharmacokinetics +17