Concepedia

A highly dl-stereoselective pinacolization of aromatic aldehydes mediated by TiCl4–Zn

Tingyou Li, Wei Cui, Jigang Liu, Jianzhang Zhao, Zongmu Wang

Chemical Communications · 2000 · 34 citations · 5 references

DOI

Concepts

Abstract

Reduction of TiCl4(THF)4 with Zn in CH2Cl2 gave a green solution, which was found to promote the reductive coupling of aromatic aldehydes to yield 1,2-diols with high threo selectivity.

References

5

Catalytic and Stoichiometric Enantioselective Addition of Diethylzinc to Aldehydes Using a Novel Chiral Spirotitanate

Beat Schmidt, Dieter Seebàch · Angewandte Chemie International Edition in English · 1991 · 172 citations

, , +10

Stereoselective Pinacol Coupling in Aqueous Media

Michael C. Barden, Jeffrey Schwartz · Journal of the American Chemical Society · 1996 · 116 citations

, , +5

Novel Concept for Efficient Transition-Metal-Catalyzed Reactions:  A Highly Diastereoselective Titanocene-Catalyzed Pinacol Coupling under Buffered Protic Conditions

Andreas Gansäuer · The Journal of Organic Chemistry · 1998 · 112 citations

, , +13

A highly dl-stereoselective pinacolization of aromatic aldehydes mediated by titanium trichloride in dichloromethane

Angelo Clerici, Laura Clerici, Ombretta Porta · Tetrahedron Letters · 1996 · 61 citations

, , +5

Reactions of lithio derivatives of carboxylic acids. 1. 3-Methyl-2-butenoic acids

Parham William E., David W. Boykin · The Journal of Organic Chemistry · 1977 · 36 citations

, , +8