Concepedia

Effect of Polysorbate 80 Concentration on Thermal and Photostability of a Monoclonal Antibody

Meera Agarkhed, Courtney O’Dell, Ming-Ching Hsieh, Jingming Zhang, J. Goldstein

AAPS PharmSciTech · 2012 · 95 citations · 19 references

DOI

Concepts

References

19

Effects of Tween 20® and Tween 80® on the Stability of Albutropin During Agitation

Danny K. Chou, Rajesh Krishnamurthy, Theodore W. Randolph et al. · Journal of Pharmaceutical Sciences · 2005 · 306 citations

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Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization

Shihong Li, Christian Schöneich, Ronald T. Borchardt · Biotechnology and Bioengineering · 1995 · 297 citations

, , +15

Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions

Narendra B. Bam, Jeffrey L. Cleland, Janet Yang et al. · Journal of Pharmaceutical Sciences · 1998 · 284 citations

, , +9

Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis

Ravuri S. K. Kishore, Astrid Pappenberger, Isabelle Bauer Dauphin et al. · Journal of Pharmaceutical Sciences · 2010 · 282 citations · Full text

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Peroxide formation in polysorbate 80 and protein stability

Emily Ha, Wei Wang, Yingfang Wang · Journal of Pharmaceutical Sciences · 2002 · 281 citations

, , +16