Concepedia

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

Michael R. Copley, Sonja Babovic, Claudia Benz, David J. H. F. Knapp, Philip Beer, David G. Kent, Stefan Wöhrer, David Q. Treloar, Christopher Day, Keegan Rowe,

Nature Cell Biology · 2013 · 344 citations · 58 references

DOI

Concepts

References

58

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Brenda J. Reinhart, Frank J. Slack, Michael Basson et al. · Nature · 2000 · 5K citations

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ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

Yifang Hu, Gordon K. Smyth · Journal of Immunological Methods · 2009 · 2.2K citations

, , +13

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

In-Kyung Park, Dalong Qian, Mark J. Kiel et al. · Nature · 2003 · 1.8K citations · Full text

, , +10

Selective Blockade of MicroRNA Processing by Lin28

Srinivas R. Viswanathan, George Q. Daley, Richard I. Gregory · Science · 2008 · 1.4K citations

, , +17

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

Marina Cavazzana, Emmanuel Payen, Olivier Nègre et al. · Nature · 2010 · 1.3K citations

, , +12