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Pancreatic enhancement after low-dose infusion of Mn-DPDP.
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1991
Year
EngineeringImaging AgentMagnetic ResonanceNew Contrast AgentBiomedical EngineeringMagnetic Resonance ImagingPancreatic CancerNuclear MedicineMolecular ImagingRadiologyMedical ImagingPancreatic EnhancementContrast AgentRadiologic ImagingMri-guided Radiation TherapyPharmacologySelective Contrast AgentIslet TransplantationMagnetic Resonance SpectroscopyPancreatic SurgeryMedicineAnesthesiology
Enhancement of the pancreas was demonstrated after low-dose (10 mumol/kg) infusion of a new contrast agent for magnetic resonance (MR) imaging, manganese dipyridoxal-diphosphate (Mn-DPDP). To the authors' knowledge, this has not been described previously. The enhancement reached a maximum of 98% +/- 13% (standard deviation) during a long period (greater than 6 hours). Mn-DPDP seems to have potential as a selective contrast agent in MR imaging of the pancreas.