Reduced Parietooccipital White Matter Glutamine Measured by Proton Magnetic Resonance Spectroscopy in Treated Graves’ Disease Patients

Abstract

The persistent reduction of glutamine in white matter, the decreasing glutamate in occipital gray matter, and the correlation with severity of the initial disease as well as with attention and concentration cognitive scores indicated that there was a persistent and possibly progressive disturbance of the glutamate glutamine cycling in Graves' disease.