Chromatin CKAP2, a New Proliferation Marker, as Independent Prognostic Indicator in Breast Cancer

Abstract

Chromatin CKAP2 is an independent prognostic marker for RFS in early-stage breast cancer, and could potentially replace the MAI in clinical evaluation of proliferation activity. Additionally, our study results suggest that the prognostic significance of proliferation activity differs among the various subgroups of breast cancer.