Concepedia

Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an In Vitro–In Vivo Scaling Methodology for the Blood–Brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone

Kathryn Ball, François Bouzom, Jean‐Michel Scherrmann, Bernard Walther, Xavier Declèves

Journal of Pharmaceutical Sciences · 2012 · 61 citations · 44 references

DOI

Concepts

References

44

Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors

Yasuo Uchida, Sumio Ohtsuki, Yuki Katsukura et al. · Journal of Neurochemistry · 2011 · 909 citations

, , +15

Atom/Fragment Contribution Method for Estimating Octanol–Water Partition Coefficients

William M. Meylan, Philip H. Howard · Journal of Pharmaceutical Sciences · 1995 · 866 citations

, , +5

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 774 citations

, , +13

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

Junichi Kamiie, Sumio Ohtsuki, Ryo Iwase et al. · Pharmaceutical Research · 2008 · 479 citations

, , +12

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

Ramzi Shawahna, Yasuo Uchida, Xavier Declèves et al. · Molecular Pharmaceutics · 2011 · 366 citations

, , +10