Celastrol from ‘Thunder God Vine’ Protects SH-SY5Y Cells Through the Preservation of Mitochondrial Function and Inhibition of p38 MAPK in a Rotenone Model of Parkinson’s Disease

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Ranjita Betarbet, Todd Sherer, Gillian M. MacKenzie et al. · Nature Neuroscience · 2000 · 3.6K citations · Full text

Biorational Pesticide, Parkinson Disease, Pesticide Resistance +6

Mechanism of Toxicity in Rotenone Models of Parkinson's Disease

Todd Sherer, Ranjita Betarbet, Claudia Testa et al. · Journal of Neuroscience · 2003 · 1.1K citations · Full text

Biochemistry, Mitochondrial Function, Dopaminergic Regions +15

A highly reproducible rotenone model of Parkinson's disease

Jason R. Cannon, Vı́ctor Tapias, Hye Mee Na et al. · Neurobiology of Disease · 2009 · 774 citations · Full text

Parkinson Disease, Neurochemical Biomarkers, Neurology +4

Molecular Ordering of the Cell Death Pathway

Arul M. Chinnaiyan, Kim Orth, Karen O’Rourke et al. · Journal of Biological Chemistry · 1996 · 585 citations · Full text

Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats

Mesbah Alam, Werner Schmidt · Behavioural Brain Research · 2002 · 472 citations

Neurophysiology, Dopaminergic Neurons, Medicine +9