Cancer · 1975 · 28 citations · 18 references
MedicineOncologySurgeryChemotherapyPediatric OncologySurgical OncologyPediatric Oncologic SurgeryPediatric SarcomasPediatric Surgical OncologyPediatric TumorsRadiation TherapySarcoma SurgeryBladder Tumor ExcisionBladder Tumors In ChildrenOrbital RhabdomyosarcomaPediatric Soft Tissue Sarcoma SurgeryRegional Lymph Node InvolvementResection Of Residual TumorRhabdomyosarcoma SurgeryRhabdomyosarcoma Treatment
Total excision remains the aim of surgical management for rhabdomyosarcomas in children, but effective adjunctive treatment for the majority of these tumors permits preservation of function and appearance in situations where formerly these were sacrificed. Control of residual tumor in microscopic quantity can now be achieved by chemotherapy in the majority of cases. The coordination of surgery, irradiation, and chemotherapy has reduced the need for ultra-radical extirpative procedures. The following conservative trends have evolved: 1) Amputations are rarely indicated for tumors of the extremities. 2) Primary irradiation for orbital tumors may obviate exenteration and save the eye. 3) Multilating excisions for head and neck tumors can often be avoided. 4) Prophylactic regional lymph node dissections are usually not indicated. 5) Primary tumors of the bladder or prostate can usually be managed by anterior exenteration.
18
The role of combined chemotherapy in the treatment of rhabdomyosarcoma in children
Ruth Heyn, Roxie Holland, William A. Newton et al. · Cancer · 1974 · 233 citations
Rhabdomyosarcoma of head and neck in children
Sarah S. Donaldson, Joseph R. Castro, Jordan R. Wilbur et al. · Cancer · 1973 · 230 citations · Full text
Prognosis in childhood rhabdomyosarcoma
Wataru W. Sutow, M. P. Sullivan, Hubert L. Ried et al. · Cancer · 1970 · 207 citations · Full text
Medicine, Oncology, Pediatrics +14
Donald Pinkel · JAMA · 1961 · 183 citations