Concepedia

Titration of Postischemic Cerebral Hypoperfusion by Variation of Ischemic Severity in a Murine Model of Stroke

Judy Huang, Louis J. Kim, Alexander Poisik, Pinsky David J., E. Sander Connolly

Neurosurgery · 1999 · 28 citations · 17 references

DOI

Abstract

Titration of the initial ischemic insult leads to corresponding variations in the magnitude of postischemic no-reflow and tissue damage. Therefore, critical control of the severity of the initial injury in studies using intraluminal suture occlusion is warranted.

References

17

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

Zhihong Huang, Paul L. Huang, Nariman Panahian et al. · Science · 1994 · 1.6K citations

, , +23

Thresholds of focal cerebral ischemia in awake monkeys

T. Hugh Jones, Richard B. Morawetz, Robert M. Crowell et al. · Journal of neurosurgery · 1981 · 1.2K citations

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

E. Sander Connolly, Christopher J. Winfree, Timothy A. Springer et al. · Journal of Clinical Investigation · 1996 · 527 citations · Full text

, , +21

Focal Cerebral Ischaemia in the Rat: 2. Regional Cerebral Blood Flow Determined by [<sup>14</sup>C]Iodoantipyrine Autoradiography following Middle Cerebral Artery Occlusion

Akira Tamura, D. Graham, James McCulloch et al. · Journal of Cerebral Blood Flow & Metabolism · 1981 · 305 citations · Full text

Procedural and Strain-related Variables Significantly Affect Outcome in a Murine Model of Focal Cerebral Ischemia

E. Sander Connolly, Christopher J. Winfree, David M. Stern et al. · Neurosurgery · 1996 · 221 citations

, , +20