Journal of Endocrinology · 1975 · 31 citations · 0 references
Life SciencesEndocrinologyPhysiologyHormone BiochemistryMetabolic RegulationMetabolismEndocrine BiochemistryHormonal Control Of MetabolismHormone MetabolismMammalian EndocrinologyRodent EndocrinologyThyroid EndocrinologyBody Weight RegulationDigestive Enzyme RegulationHormonal Regulation Of DigestionMaltase ActivityMucosal Enzyme RegulationSmall Intestine AnatomyThyroid Hormone PhysiologyThyroidectomy Physiology
Adrenalectomy performed on 14-day-old rats delayed the usual increase of sucrase and maltase activity as well as the decrease of acid beta-galactosidase, beta-glucuroindase and N-acetyl-beta-glucosaminidase activity during the third postnatal week. Since these changes were only delayed, the role of the thyroid was explored. Thyroidectomy performed simultaneously with adrenalectomy on 14-day-old rats did not influence the increase in body weight and growth of the small intestine (already slowed down by adrenalectomy), but caused a further substantial delay in the maturation of the enzyme profile of the small intestine. Our results indicate that the thyroid is involved in regulation of the hydrolases studied.