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Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

Neurodegenerative DiseasesProtein SecretionMolecular NeuroscienceAlzheimer's DiseaseMedicineMolecular BiologyDegenerative PathologyNeurochemical BiomarkersDisease MutationsProtein MisfoldingSystems Biologyγ-Secretase ModulatorsEpsilon-cleavage-dependent Aicd ProductionProtective Mechanisms