Indian Journal of Pharmacology · 2009 · 14 citations · 9 references
Substance AbuseAccidental IngestionMedicineSkeletal Muscle RelaxantForensic ToxicologyPediatricsGastroenterologyBaclofen IntoxicationPoisoningToxicologyPharmacotherapyAnesthesiaPharmacologyBaclofen OverdoseClinical ToxicologyAnesthesiology
Baclofen is a skeletal muscle relaxant, used to control spasticity in both adults and children with neuromuscular disorders. Several cases of baclofen overdose have been reported, but only a small number have involved children. We report a 3-year-old girl with accidental ingestion of baclofen, who presented with coma, bradycardia and hypotension. She recovered within 24 hours with supportive treatment. The case emphasizes the importance of warning parents about the potential toxicity of baclofen when the drug is prescribed to a family member.
9
Baclofen Overdose: Drug Experimentation in a Group of Adolescents
Holly Perry, Robert O. Wright, Michael W. Shannon et al. · PEDIATRICS · 1998 · 149 citations
Complications of baclofen overdosage
Karabi Ghose, K M Holmes, K Matthewson · Postgraduate Medical Journal · 1980 · 92 citations · Full text
Baclofen intoxication: report of four cases and review of the literature.
T H Lee, S S Chen, S L Su et al. · PubMed · 1992 · 77 citations