Concepedia

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

Rika Hoshino, Yuji Chatani, Takao Yamori, Takashi Tsuruo, Hiroya Oka, Osamu Yoshida, Yutaka Shimada, Shigeki Arii, Hiromi Wada, Jiro Fujimoto,

Oncogene · 1999 · 693 citations · 26 references

DOI

Concepts

References

26

The MAPK signaling cascade

Rony Seger, Edwin G. Krebs · The FASEB Journal · 1995 · 3.4K citations

, , +17

The mitogen-activated protein kinase signal transduction pathway

Roger J. Davis · Journal of Biological Chemistry · 1993 · 2.2K citations · Full text

, , +12

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

Sally A. Cowley · Cell · 1994 · 2K citations

, , +8

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Teri G. Boulton, Steven H. Nye, David J. Robbins et al. · Cell · 1991 · 1.9K citations

, , +10

Autocrine Secretion and Malignant Transformation of Cells

Michael B. Sporn, George J. Todaro · New England Journal of Medicine · 1980 · 1.4K citations

, , +17