Concepedia

Novel Synthesis of Mercaptopurine and Pentaaza-as-Indacene Analogues: Reaction of [Bis(methylthio)methylene]malononitrile and Ethyl 2-Cyano-3,3-bis(methylthio)acrylate with 5-Aminopyrazoles

Galal H. Elgemeie, Samia E El-Ezbawy, Hosny A. Ali, Abdel-Kader Mansour

Bulletin of the Chemical Society of Japan · 1994 · 56 citations · 4 references

DOI

Concepts

Abstract

Abstract A novel synthesis of 7-methylthiopyrazolo[1,5-a]pyrimidines via reaction of [bis(methylthio)methylene]malononitrile and ethyl 2-cyano-3,3-bis(methylthio)acrylate with 5-aminopyrazoles is reported and the synthetic potential of the method is demonstrated.

References

4

Nucleic acid-related compounds. 58. Periodinane oxidation, selective primary deprotection, and remarkably stereoselective reduction of tert-butyldimethylsilyl-protected ribonucleosides. Synthesis of 9-(.beta.-D-xylofuranosyl)adenine or 3'-deuterioadenosine from adenosine

Morris J. Robins, Vicente Sámano, Mark D. Johnson · The Journal of Organic Chemistry · 1990 · 77 citations

, , +17

Reactions with 3,5‐Diaminopyrazoles: New Routes to Pyrazolo[1,5‐α]pyrimidines

Galal H. Elgemeie, Nahed M. Fathy, Laila M. Faddah et al. · Archiv der Pharmazie · 1991 · 37 citations

, , +8

Studies on aminoazoles: Synthesis of Pyrazolo[1,5‐a]‐pyrimidines and their aza derivatives

Galal H. Elgemeie, Ahmed H. Elghandour, Hamdy M. Elshimy · Journal für praktische Chemie · 1989 · 34 citations

, , +9

Reactiohs with α -thiocarbamoylcinnamonitriles: Synthesis of pyrazolo [1,5-a] pyrimidines

Sohair Mohamed Hussain, A. M. EL‐REEDY, Salwa A. Elsharabasy · Tetrahedron · 1988 · 28 citations

, , +6