Concepedia

Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain

David J. Loane, Brian F. Deighan, Rachael M. Clarke, Rebecca J. Griffin, Aileen Lynch, Marina A. Lynch

Neurobiology of Aging · 2007 · 88 citations · 64 references

DOI

Concepts

References

64

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

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Generation and Analysis of Interleukin-4 Deficient Mice

Ralf Kühn, Klaus Rajewsky, Werner Müller · Science · 1991 · 1.3K citations

, , +17

PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

Ajay Chawla, Yaacov Barak, László Nagy et al. · Nature Medicine · 2001 · 1.1K citations

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Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

Marcus E. Risner, Ann M. Saunders, Jill F.B. Altman et al. · The Pharmacogenomics Journal · 2006 · 681 citations

, , +12

Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone: A Preliminary Study

G. Stennis Watson · American Journal of Geriatric Psychiatry · 2005 · 599 citations

, , +16