Age-dependent changes in transmembrane signalling: Identification of G proteins in human lymphocytes and polymorphonuclear leukocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

PubMed · 1968 · 5.3K citations

Life Sciences, Cell Biology, Immunology +6

G proteins and dual control of adenylate cyclase

Alfred G. Gilman · Cell · 1984 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +12

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans.

Steven Gillis, Robert W. Kozak, Marco Durante et al. · Journal of Clinical Investigation · 1981 · 474 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

Toshiaki Katada, Masayuki Oinuma, M Ui · Journal of Biological Chemistry · 1986 · 315 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8