Adrenergic receptor of the alpha1-subtype mediates the activation of the glycogen phosphorylase in normal rat liver

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Isolation of an organ specific protein antigen from cell-surface membrane rat liver

David M. Neville · Biochimica et Biophysica Acta (BBA) - Protein Structure · 1968 · 878 citations

Life Sciences, Biochemistry, Molecular Biology +12

A functional basis for classification of α-adrenergic receptors

Spencer Berthelsen, William A. Pettinger · Life Sciences · 1977 · 802 citations

Medicine, Pharmacology, Physiology +10

Relative pre- and postsynaptic potencies of ?-adrenoceptor agonists in the rabbit pulmonary artery

Klaus Starke, Takahiko Endo, H. D. Taube · Naunyn-Schmiedeberg s Archives of Pharmacology · 1975 · 455 citations

Medicine, Pharmacology, Pharmacodynamics +8

SELECTIVITY OF BLOCKING AGENTS FOR PRE‐ AND POSTSYNAPTIC α‐ADRENOCEPTORS

John C. Doxey, C. F. C. SMITH, Julie M. Walker · British Journal of Pharmacology · 1977 · 424 citations · Full text

Medicine, Pharmacology, Cardiovascular Pharmacotherapy +12