Drug Metabolism and Pharmacokinetics of 4-Substituted Methoxybenzoyl-aryl-thiazoles

Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

Yan Lü, Chien‐Ming Li, Zhao Wang et al. · Journal of Medicinal Chemistry · 2009 · 183 citations · Full text

Pharmacy, Oncology, Pharmacology +16

<i>In Vivo</i>Pharmacokinetics of Felodipine Predicted from<i>in Vitro</i>Studies in Rat, Dog and Man

Catharina Bäärnhielm, Helena Dahlbäck, Inger Skånberg · Acta Pharmacologica et Toxicologica · 1986 · 98 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Determination of microsome and hepatocyte scaling factors for<b><i>in vitro</i></b>/<b><i>in vivo</i></b>extrapolation in the rat and dog

Roy E. Smith, Rhys D.O. Jones, Peter Ballard et al. · Xenobiotica · 2008 · 57 citations

Pharmacy, Biochemistry, Pharmacology +14

Reduction of Site-Specific CYP3A-Mediated Metabolism for Dual Angiotensin and Endothelin Receptor Antagonists in Various in Vitro Systems and in Cynomolgus Monkeys

Hongjian Zhang, Donglu Zhang, Wenying Li et al. · Drug Metabolism and Disposition · 2007 · 17 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude mice.

Lichun Sun, Natalya I. Vasilevich, Joseph A. Fuselier et al. · PubMed · 2004 · 17 citations

Medicine, Medicinal Chemistry, Pharmacology +10