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Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR

Frb DomainSignal TransductionBiochemistryG Protein-coupled ReceptorNatural SciencesPhosphatidic AcidReceptor Tyrosine KinaseMechanism Of ActionMolecular BiologyBiochemical InteractionProtein PhosphorylationNovel ClassCellular BiochemistryMedicineCell SignalingSmall Molecules