Concepedia

Metal-free in situ sp<sup>3</sup>, sp<sup>2</sup>, and sp C–H functionalization and oxidative cross coupling with benzamidines hydrochloride: a promising approach for the synthesis of α-ketoimides

Hanuman P. Kalmode, Kamlesh S. Vadagaonkar, Atul Chaskar

RSC Advances · 2014 · 41 citations · 77 references

DOI

Concepts

Abstract

A new metal-free tandem protocol for the synthesis of α-ketoimides <italic>via</italic> sp<sup>3</sup>, sp<sup>2</sup>, and sp C–H functionalization followed by oxidative cross coupling with benzamidines hydrochloride using catalytic iodine with TBHP in DMSO has been developed.

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