Direct and Waste‐Free Amidations and Cycloadditions by Organocatalytic Activation of Carboxylic Acids at Room Temperature

Abstract

Taming carboxylic acids: ortho-Iodo- and ortho-bromophenylboronic acids are exceptional organocatalysts in atom-economical amidations between free carboxylic acids and amines, including functionalized ones, and can also provide LUMO-lowering activation in [4+2] cycloadditions of α,β-unsaturated carboxylic acids. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z705468_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.