Templating Effect of Lipid Membranes on Alzheimer's Amyloid Beta Peptide

Abstract

Electrostatic influence on peptide association: The first X-ray reflectivity and grazing-incidence X-ray diffraction study on amyloid beta peptide and lipid monolayers provides insight into the differences in the interaction of the peptide with cationic and anionic monolayers (see picture). A unique templating effect is observed in the latter case.