Concepedia
Toxicology · 2000 · 94 citations · 38 references
Life SciencesCell BiologyToxicologyApoptosisCell SignalingMechanisms Of ToxicityApoptotic SignalingBcl-2 Family ProteinsCaspase ActivationCell DeathMetal ToxicityProgrammed Cell DeathCadmium Toxicity MechanismsCadmium-induced ApoptosisCaspase-mediated Apoptosis
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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text
Life Sciences, Biochemistry, Molecular Biology +17
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations
Life Sciences, Cell Biology, Molecular Biology +13
A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations
Life Sciences, Immunology, Molecular Biology +12
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
Cell · 1993 · 2.5K citations · Full text
Life Sciences, Genetics, Molecular Biology +10
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations
Life Sciences, Biochemistry, Molecular Biology +10