One-step synthesis of 12-ketoursodeoxycholic acid from dehydrocholic acid using a multienzymatic system

One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products

Kirill A. Datsenko, Barry L. Wanner · Proceedings of the National Academy of Sciences · 2000 · 15.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

PCR-targeted <i>Streptomyces</i> gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

Bertolt Gust, Gregory L. Challis, Kay Fowler et al. · Proceedings of the National Academy of Sciences · 2003 · 1.4K citations

Life Sciences, Biotechnology, Microbiology +14

Strategies for achieving high-level expression of genes in Escherichia coli.

Savvas C. Makrides · Microbiological Reviews · 1996 · 577 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis*1

B COMBES · Hepatology · 1995 · 270 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Reduction of Steroid Ketones and other Carbonyl Compounds by Modified Wolff--Kishner Method

not available Huang-Minlon · Journal of the American Chemical Society · 1949 · 249 citations

Natural Sciences, Biochemistry, Chemistry +8