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PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase

Signal TransductionDna BindingSignaling PathwayNatural SciencesQuiescent CellsMolecular BiologyParp-1 Binds E2f-1Cellular BiochemistryGene ExpressionMedicineCell BiologyTranscription Regulation