African American Renal Transplant Recipients (RTR) Require Higher Tacrolimus Doses to Achieve Target Levels Compared to White RTR: Does Clotrimazole Help?

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

Kenneth S. Lown, Robert R. Mayo, Alan B. Leichtman et al. · Clinical Pharmacology & Therapeutics · 1997 · 682 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery

Mary F. Hébert · Advanced Drug Delivery Reviews · 1997 · 286 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

RACIAL DIFFERENCES IN RENAL TRANSPLANTATION AFTER IMMUNOSUPPRESSION WITH TACROLIMUS VERSUS CYCLOSPORINE1

John F. Neylan · Transplantation · 1998 · 275 citations

Medicine, Nephrology, Surgery +14

Cytochrome P450 3A4 and P‐glycoprotein Expression in Human Small Intestinal Enterocytes and Hepatocytes: A Comparative Analysis in Paired Tissue Specimens

Oliver von Richter, Oliver Burk, Martin F. Fromm et al. · Clinical Pharmacology & Therapeutics · 2004 · 257 citations

Medicine, Biochemistry, Pharmacology +17

Patient noncompliance: a major cause of late graft failure in cyclosporine-treated renal transplants.

Ralph Didlake, K Dreyfus, Ronald H. Kerman et al. · PubMed · 1988 · 222 citations

Medicine, Nephrology, Pharmacotherapy +14