Annals of Internal Medicine · 1981 · 416 citations · 28 references
MedicineJurisprudenceApoptosisPalliative CareBirth-death ProcessesCause Of Death DeterminationCell DeathDeath DeterminationManner Of Death ClassificationManner Of Death DeterminationDeath Criteria
Death has traditionally been defined as the permanent cessation of whole‑organism function. The authors propose that total irreversible loss of whole‑brain function is the sole criterion of death and suggest a statutory definition that permits physicians to declare death according to customary practices. When artificial ventilation is present, only fully validated brain dysfunction tests can confirm death, whereas in its absence permanent loss of cardiopulmonary function is sufficient, and the authors’ statutory definition accommodates both scenarios.
The permanent cessation of functioning of the organism as a whole is the definition underlying the traditional understanding of death. We suggest the total and irreversible loss of functioning of the whole brain as the sole criterion of death; this has always been an implicit criterion of death. If artificial ventilation is present, only completely validated brain dysfunction tests should be used to show that this criterion of death is satisfied. In most cases without artificial ventilation, permanent loss of cardiopulmonary function is sufficient. We propose a statutory definition of death based on the criterion of total and irreversible cessation of whole brain functions but allowing physicians to declare death according to their customary practices in most cases.
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PERSISTENT VEGETATIVE STATE AFTER BRAIN DAMAGE
Bryan Jennett, Fred Plum · The Lancet · 1972 · 1.2K citations
[The depassed coma (preliminary memoir)].
P Mollaret, M Goulon · PubMed · 1959 · 349 citations
Robert S. Morison · Science · 1971 · 213 citations
An Appraisal of the Criteria of Cerebral Death
JAMA · 1977 · 119 citations