<i>babA2-</i> and <i>cagA</i> -Positive <i>Helicobacter pylori</i> Strains Are Associated with Duodenal Ulcer and Gastric Carcinoma in Brazil

Abstract

The babA2 and cagA genes were investigated in 208 Brazilian Helicobacter pylori strains. A strong association between babA2 and duodenal ulcer or gastric carcinoma was observed, even after adjusting for confounding factors, such as age, gender, and cagA status. cagA-positive strains were also independently associated with H. pylori-related diseases.