Raised concentrations of antibodies to cardiolipin in patients receiving dialysis.

Abstract

to be non-linear; terms and YEAR cubed (p= 004) significantly improved the fit of the model.The final model fitted well: residuals were appropriately distributed, no additional regression terms were needed, and a leverage analysis indicated that the results had not been distorted by unrepresentative data points.In both sexes the fitted suicide rate for 1975 in- creased consistently with increasing age.Males exhibited a significantly higher rate of suicide than females within all age strata.In males the fitted rate ranged from 61-9 deaths per million per annum (95% confidence interval 55 3 to 69 3) in the youngest age group to 189-2 (163 0 to 219 5) deaths per million per annum in the oldest.In females the equivalent range was from 28-4 (23-9 to 33 7) to 107-2 (93-1 to 1234) deaths per million per annum.Among males in each of the age groups 15-24, 25-34, and 35-44 the suicide rate increased significantly (p<0-0001) between 1975 and 1987 (figure).No significant changes were observed in the older age groups.In sharp contrast, all females in all age groups showed a decline in suicide rate, ranging from a 33% fall (p=0O002) in the age group 35-44 to a 17% fall (p=0 055) in the group 25-34.