Gene–gene interaction of <i>BLK</i>, <i>TNFSF4</i>, <i>TRAF1</i>, <i>TNFAIP3</i>, and <i>REL</i> in systemic lupus erythematosus

Abstract

The results of this study provide evidence of the possible gene-gene interactions of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in SLE, which may represent a synergic effect of T cells and B cells through the NF-κB pathway in determining immunologic aberration.