Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women

Gregory J. Tranah, Terri Blackwell, Katie L. Stone, Sonia Ancoli‐Israel, Misti L. Paudel, Kristine E. Ensrud, Jane A. Cauley, Susan Redline, Teresa A. Hillier, Steven R. Cummings,

Annals of Neurology · 2011 · 511 citations · 71 references

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Abstract

Older, healthy women with decreased circadian activity rhythm amplitude and robustness, and delayed rhythms have increased odds of developing dementia and MCI. If confirmed, future studies should examine whether interventions (physical activity, bright light exposure) that influence activity rhythms will reduce the risk of cognitive deterioration in the elderly.

References

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