Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene–transduced chondrocytes with adeno‐associated virus vector

Abstract

These results demonstrated that gene transfer to chondrocytes by an ex vivo method was established with the AAV vector, and transplantation of bFGF gene-transduced chondrocytes had a clear beneficial effect on the repair of rabbit articular cartilage defects.