Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Medicine, Biostatistics, Pharmacology +17

A novel biologically active seleno-organic compound—1

A. Müller, Enrique Cadenas, Peter Gräf et al. · Biochemical Pharmacology · 1984 · 826 citations

Pharmacy, Chemistry, Medicinal Chemistry +4

A novel biologically active seleno-organic compound—II

Albrecht Wendel, Martina Fausel, Hasan Safayhi et al. · Biochemical Pharmacology · 1984 · 429 citations

Pharmacy, Chemistry, Medicinal Chemistry +5

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

Seppo Ylä‐Herttuala, Margaret Rosenfeld, S Parthasarathy et al. · Proceedings of the National Academy of Sciences · 1990 · 428 citations

Life Sciences, Pathobiology, Pathology +15

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

S Parthasarathy, Eberhard Wieland, Daniel Steinberg · Proceedings of the National Academy of Sciences · 1989 · 413 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +15