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A selectable system for mutation detection in the Big Blue® lacI transgenic mouse system: what happens to the mutational spectra over time

Knockout MouseBig Blue®EngineeringTransgenic Mouse ModelsSomatic VariantMedicineGeneticsMutation DetectionGenetic EngineeringMolecular GeneticsTransgenic Mouse SystemDisease Gene IdentificationSystems BiologyMolecular DiagnosticsGenome EditingMutagenesis