Development of five membered heterocyclic frameworks via [3+2] cycloaddition reaction in an aqueous micellar system

Abstract

A series of novel dihydropyrrolo[2,1-<italic>a</italic>]isoquinolines and dihydropyrrolo[1,2-<italic>a</italic>]quinolines have been synthesized from isoquinolines/quinolines, various substituted phenacyl bromides and substituted dialkylacetylenedicarboxylates <italic>via</italic> [3+2] cycloaddition reaction.