Benzofuran derivatives as a novel class of inhibitors of mTOR signaling

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.6K citations · Full text

Medicine, Oncology, Pharmacology +16

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

Tweeny R. Kau, Frank C. Schroeder, Shivapriya Ramaswamy et al. · Cancer Cell · 2003 · 327 citations · Full text

Medicine, Molecular Biology, Oncology +15

Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin

Shripad V. Bhagwat, Prafulla C. Gokhale, Andrew P. Crew et al. · Molecular Cancer Therapeutics · 2011 · 201 citations

Medicine, Oncology, Pharmacology +13

A Direct Approach to 5-Hydroxybenzofurans via a Platinum-Catalyzed Domino Rearrangement/5-<i>endo</i>-<i>dig</i> Cyclization Reaction of Quinols

Ikyon Kim, Kyungsun Kim, Jungeun Choi · The Journal of Organic Chemistry · 2009 · 57 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Reductive, selective deoxygenation of acylbenzo[b]furans, aromatic aldehydes and ketones with NaBH3CN-TMSCl

Vernon G. S. Box, Panayiotis C. Meleties · Tetrahedron Letters · 1998 · 24 citations

Natural Sciences, Chemical Engineering, Chemistry +14